This symbolizes why I see Trump as such a danger. Among his flood of tweets yesterday, Trump included the one I have reproduced below. The tweet from a Florida man was accompanied by a video showing a Florida bar (open air; looked like on a pier) was very crowded. The guy shooting it was bragging about the lack of social distancing and the wearing of masks. Trump retweeted it without comment. How in the world is that responsible behavior, much less leadership, from a President? Party on, Wayne. Party on, Garth.
This symbolizes why I see Trump as such a danger. Among his flood of tweets yesterday, Trump included the one I have reproduced below. The tweet from a Florida man was accompanied by a video showing a Florida bar (open air; looked like on a pier) was very crowded. The guy shooting it was bragging about the lack of social distancing and the wearing of masks. Trump retweeted it without comment. How in the world is that responsible behavior, much less leadership, from a President? Party on, Wayne. Party on, Garth.
Actually my understanding is that getting in early turns off or drastically slows down our antibody generation, because what the virus does in high risk (pulmonary anyway) is put your immune system into overdrive and your own antibodies kill you. It is basically keeping you out of your defense and the virus itself is not so bad by itself that you can be managed through the infection staying out of an ICU, which is the name of the game if you go down, at least for me.
I could be close or half right with this explanation. It's just a summary of all the listening I've been doing lately.
And with anything, getting started STAT makes all the difference in the outcome.
Me, I'm hoping to pick up a plasma antibody fix. That is what I want the most, sitting where I am right now. I could then relax and get on with it.
Funny to think that cancer is the least of my problems right now.
yeah i think it gets a head start and then springs into action
if your immune system over responds i think could trigger a cytokine storm
Location: Perched on the precipice of the cauldron of truth
Posted:
May 15, 2020 - 12:44pm
kurtster wrote:
Actually my understanding is that getting in early turns off or drastically slows down our antibody generation, because what the virus does in high risk (pulmonary anyway) is put your immune system into overdrive and your own antibodies kill you. It is basically keeping you out of your defense and the virus itself is not so bad by itself that you can be managed through the infection staying out of an ICU, which is the name of the game if you go down, at least for me.
I could be close or half right with this explanation. It's just a summary of all the listening I've been doing lately.
And with anything, getting started STAT makes all the difference in the outcome.
Me, I'm hoping to pick up a plasma antibody fix. That is what I want the most, sitting where I am right now. I could then relax and get on with it.
Funny to think that cancer is the least of my problems right now.
I wonder who is getting plasma antibodies/how they become available and where. I would assume that they are not plentiful or readily available. I saw a news story last night about a nurse at Mt. Sinai in NYC who got Covid and was staying at home recovering when it worsened and she was hospitalized at Mt. Sinai. She said her son suggested plasma antibodies and the mother received that treatment and said she began recovering within 24 hours. Unclear whether the son was a doctor or otherwise in the health field, but made me wonder why the treating doctors would not be the ones recommending the treatment with plasma antibodies?
it doesn't eliminate the virus completely or all at once
it drops the viral load to lower levels and gives your body a better opportunity to (not) respond
so in most people with healthy immune systems that would or should produce antibodies
another angle is the distributed bio type strategy of just producing the antibodies and giving that to people
if your immune system is overwhelmed or isn't functioning properly it may not produce antibodies
so the antibody treatment is great (and it is usually much easier and faster to market)
Actually my understanding is that getting in early turns off or drastically slows down our antibody generation, because what the virus does in high risk (pulmonary anyway) is put your immune system into overdrive and your own antibodies kill you. It is basically keeping you out of your defense and the virus itself is not so bad by itself that you can be managed through the infection staying out of an ICU, which is the name of the game if you go down, at least for me.
I could be close or half right with this explanation. It's just a summary of all the listening I've been doing lately.
And with anything, getting started STAT makes all the difference in the outcome.
Me, I'm hoping to pick up a plasma antibody fix. That is what I want the most, sitting where I am right now. I could then relax and get on with it.
Funny to think that cancer is the least of my problems right now.
Location: Perched on the precipice of the cauldron of truth
Posted:
May 15, 2020 - 10:39am
This symbolizes why I see Trump as such a danger. Among his flood of tweets yesterday, Trump included the one I have reproduced below. The tweet from a Florida man was accompanied by a video showing a Florida bar (open air; looked like on a pier) was very crowded. The guy shooting it was bragging about the lack of social distancing and the wearing of masks. Trump retweeted it without comment. How in the world is that responsible behavior, much less leadership, from a President? Party on, Wayne. Party on, Garth.
Is it ethical to intentionally infect volunteers with the coronavirus to test the effectiveness of vaccines? Yes, argues our expert Dr. Stanley A. Plotkin. In this special report, he gives an overview of the advantages, risks and ethical questions of human challenge studies about COVID-19.
Published online 2014 Oct 1 Zinc ions enhance chloroquines' cytotoxicity
To determine whether the addition of zinc and chloroquine can kill cancer cells more effectively, A2780 cells were treated with increasing concentrations of chloroquine in the presence of 25 µM zinc chloride for 72 hours. Cell viability analysis indicated that zinc ions significantly enhanced chloroquine's cytotoxicity in this model system
there are quite few drugs that are ionophores that are in the que to be investigated
and yeah if you take some sort of ionophore medication for covid-19 it should used with zinc and it should be used early as possible
some are using it in combination with other known antiviral drugs
i'm pretty sure that there are several countries that are using chloroquine or hydroxychloroquine on a large scale
i think this may be for several reasons
it's available, it's inexpensive and they may be somewhat comfortable using it
and it could be all that they've got at the moment
viral load is a big deal and it appears they (hcq and zinc) could help with that
Published online 2014 Oct 1 Zinc ions enhance chloroquines' cytotoxicity
To determine whether the addition of zinc and chloroquine can kill cancer cells more effectively, A2780 cells were treated with increasing concentrations of chloroquine in the presence of 25 µM zinc chloride for 72 hours. Cell viability analysis indicated that zinc ions significantly enhanced chloroquine's cytotoxicity in this model system
Promising new preprint from UK+US researchers showing that a single injection of the Oxford adenovirus that encodes the #COVID19#SARSCoV2 spike protein (ChAdOx1) serves as an effective vaccine in monkeys, blocking pneumonia & greatly lowering viral load.ðhttps://t.co/JySG4SojYzpic.twitter.com/RkyrWpuC7H
I was thinking about something like this earlier this week or so. I thought how nice it is not to live in some touristy spot right now. Up until Sea World of Aurora closed back in 2007 and then Geauga Lake went down shortly after, this neck of the woods has reverted to nothing special. Just local folks. I've lived in touristy spots around the country most of my life until Sea World went down here and even though it was seasonal back here, it still was a pain in the butt being a local and having to put up with all of the confused out of towners. Now they are potential disease vectors.
I totally understand your concerns. I would be very wary of strangers coming in and stirring things up literally. I dunno. It's a tightrope act for making any decisions. How dependent is your local economy on tourism ?