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Index » Radio Paradise/General » General Discussion » COVID-19 Page: Previous  1, 2, 3 ... 327, 328, 329 ... 395, 396, 397  Next
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R_P

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Gender: Male


Posted: Apr 17, 2020 - 4:45pm


BlueHeronDruid

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Location: Заебани сме луѓе


Posted: Apr 17, 2020 - 3:14pm



 black321 wrote:


 BlueHeronDruid wrote:


 
 
In the face of this. All positives were completely asymptomatic.


So we really have no idea how many people are actively out there spreading the virus.
 

I wonder about the effectiveness of the tests...what % false positive
 
Here's a good read on that subject.


kurtster

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Location: where fear is not a virtue
Gender: Male


Posted: Apr 17, 2020 - 2:30pm

 R_P wrote:
New study indicates coronavirus can jump from the dead to the living
Are the bodies of COVID-19 victims infectious? Officials preparing huge temporary morgues and mass graves aren't taking any chances
 
Not surprised at all.  Infections from corpses with other diseases is rather common and has long been known.
THE INFECTION HAZARDS OF HUMAN CADAVERS

The Recently Dead

The diseases and organisms which may pose particular risks vary in different parts of the world but include tuberculosis; streptococcal infection; gastro-intestinal organisms; Creutzfeldt-Jakob disease; viral hepatitis, HIV infection, MERS, and other viral infections (particularly viral haemorrhagic fevers such as Lassa, Marburg, or Ebola); and possibly meningitis and septicaemia (especially meningococcal) (seeTable 41.2). In general, good practice, the use of appropriate protective clothing, will greatly reduce the risk of acquiring infection, but some additional precautions may be advisable for particular infections, for example, when dealing with infectious agents transmitted by a vector that is resident on the deceased (e.g. body lice and typhus, fleas, and plague), as these will leave the deceased and may move onto those handling the cadaver putting them at risk.

black321

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Location: An earth without maps
Gender: Male


Posted: Apr 17, 2020 - 1:49pm



 BlueHeronDruid wrote:


 
 
In the face of this. All positives were completely asymptomatic.


So we really have no idea how many people are actively out there spreading the virus.
 

I wonder about the effectiveness of the tests...what % false positive
Proclivities

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Location: Paris of the Piedmont
Gender: Male


Posted: Apr 17, 2020 - 12:36pm



 R_P wrote:
New study indicates coronavirus can jump from the dead to the living
Are the bodies of COVID-19 victims infectious? Officials preparing huge temporary morgues and mass graves aren't taking any chances
 

One would think it was protocol to wear protective gear during the mass burials, apparently not everywhere.  When the inmates buried the early AIDS victims on Hart Island in NYC they wore haz-mat style gear - it wasn't known how it was transmitted until later on.  I imagine (hope) whoever is doing the burials out there now is doing the same.
R_P

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Gender: Male


Posted: Apr 17, 2020 - 12:16pm

New study indicates coronavirus can jump from the dead to the living
Are the bodies of COVID-19 victims infectious? Officials preparing huge temporary morgues and mass graves aren't taking any chances
BlueHeronDruid

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Location: Заебани сме луѓе


Posted: Apr 17, 2020 - 10:28am



 steeler wrote:
Idiot-in-Chief is encouraging protesters defying stay-at-home restrictions in Michigan, Minnesota, and Virginia.

 
In the face of this. All positives were completely asymptomatic.


So we really have no idea how many people are actively out there spreading the virus.
steeler

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Location: Perched on the precipice of the cauldron of truth


Posted: Apr 17, 2020 - 9:40am

Idiot-in-Chief is encouraging protesters defying stay-at-home restrictions in Michigan, Minnesota, and Virginia.

black321

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Location: An earth without maps
Gender: Male


Posted: Apr 17, 2020 - 8:34am

Gilead had a promising trial for remdesivir; cautious optimisim.

ScottFromWyoming

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Location: Powell
Gender: Male


Posted: Apr 17, 2020 - 8:19am



 Lazy8 wrote:
Red_Dragon wrote:
The best evidence for it's ineffectiveness it the fact that Trump said it works. Bigly.


Coming out of Trump's mouth doesn't necessarily make it wrong, but if you're looking for sound advice you should definitely consider the source.

You might find a diamond in the cat box but it isn't the first place to look.
 

*takes off gloves and thinks "now what?"*
Lazy8

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Location: The Gallatin Valley of Montana
Gender: Male


Posted: Apr 17, 2020 - 8:08am

Red_Dragon wrote:
The best evidence for it's ineffectiveness it the fact that Trump said it works. Bigly.


Coming out of Trump's mouth doesn't necessarily make it wrong, but if you're looking for sound advice you should definitely consider the source.

You might find a diamond in the cat box but it isn't the first place to look.
ScottFromWyoming

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Location: Powell
Gender: Male


Posted: Apr 17, 2020 - 8:06am

I guess they had to pass it to find out what was in it.



Millionaires receive $1.7m in coronavirus relief due to loophole

Red_Dragon

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Location: Dumbf*ckistan


Posted: Apr 17, 2020 - 7:49am



 Lazy8 wrote:

Hydroxychloroquine Trial for Treating COVID-19 Disappoints

"The best available evidence does not support the use of hydroxychloroquine in COVID-19."

A just-reported Chinese study compares the clinical outcomes of COVID-19 patients treated with hydroxychloroquine with those of patients receiving standard of care. The results, alas, are disappointing.

I summarized that study in my roundup yesterday of COVID-19 therapeutic research, pointing out that this randomized controlled trial of 150 patients "found no difference in the rate of viral load reduction or symptom alleviation between the group treated with hydroxychloroquine and the one that had not been." Now the University of Vermont pulmonologist Josh Farkas has published his own analysis of the results, delving more deeply into the data.

The patients in both arms of the study were well-matched demographically and clinically, Farkas notes. Most suffered relatively mild cases of the disease, and treatment was initiated fairly late—about 16 to 17 days after disease onset. Twenty-eight days into the trial, the researchers found essentially no difference between the two cohorts with respect to the percent of patients in which the virus was undetectable.




Tang et al.


Farkas adds:

This endpoint most directly addresses the question: does hydroxychloroquine exert anti-viral activity in vivo? The answer seems to be: nope. Even if the drug were administered too late to affect the clinical course of the infection, if it exerted any anti-viral activity then we might expect to see that effect here. If anything, there might be a trend towards delayed viral clearance in patients treated with hydroxychloroquine.

The study also found that fever and respiratory symptoms did not abate any faster in patients who had been treated with hydroxychloroquine.

 
The best evidence for it's ineffectiveness it the fact that Trump said it works. Bigly.

Lazy8

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Location: The Gallatin Valley of Montana
Gender: Male


Posted: Apr 17, 2020 - 7:13am

Hydroxychloroquine Trial for Treating COVID-19 Disappoints

"The best available evidence does not support the use of hydroxychloroquine in COVID-19."

A just-reported Chinese study compares the clinical outcomes of COVID-19 patients treated with hydroxychloroquine with those of patients receiving standard of care. The results, alas, are disappointing.

I summarized that study in my roundup yesterday of COVID-19 therapeutic research, pointing out that this randomized controlled trial of 150 patients "found no difference in the rate of viral load reduction or symptom alleviation between the group treated with hydroxychloroquine and the one that had not been." Now the University of Vermont pulmonologist Josh Farkas has published his own analysis of the results, delving more deeply into the data.

The patients in both arms of the study were well-matched demographically and clinically, Farkas notes. Most suffered relatively mild cases of the disease, and treatment was initiated fairly late—about 16 to 17 days after disease onset. Twenty-eight days into the trial, the researchers found essentially no difference between the two cohorts with respect to the percent of patients in which the virus was undetectable.




Tang et al.


Farkas adds:

This endpoint most directly addresses the question: does hydroxychloroquine exert anti-viral activity in vivo? The answer seems to be: nope. Even if the drug were administered too late to affect the clinical course of the infection, if it exerted any anti-viral activity then we might expect to see that effect here. If anything, there might be a trend towards delayed viral clearance in patients treated with hydroxychloroquine.

The study also found that fever and respiratory symptoms did not abate any faster in patients who had been treated with hydroxychloroquine.

Coaxial

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Location: Comfortably numb in So Texas
Gender: Male


Posted: Apr 16, 2020 - 8:57pm

 steeler wrote:
Now, after listening to the plan for opening the country, why do I feel that I am either too stupid to understand it or there is something troubling?
 
Every time we listen to him we come away just a little more stupid even if it as we change channels. A microsecond of viewing kills x amount of our brain cells.{#Stop}
steeler

steeler Avatar

Location: Perched on the precipice of the cauldron of truth


Posted: Apr 16, 2020 - 8:26pm

Now, after listening to the plan for opening the country, why do I feel that I am either too stupid to understand it or there is something troubling?
miamizsun

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Location: (3283.1 Miles SE of RP)
Gender: Male


Posted: Apr 16, 2020 - 5:53pm

Researchers to test asthma drug to treat Covid-19

Local infectious disease specialists said they would evaluate the potential of asthma treatment ciclesonide (brand name: Alvesco) against the new coronavirus.

Recently, the Institute Pasteur Korea (IPK) suggested that ciclesonide and niclosamide, an ingredient of animal tapeworm drug, as two medicines with a possible potency against the deadly virus that has no cure or vaccine.

Researchers at the IPK said they narrowed down 48 drugs authorized by the U.S. Food and Drug Administration to 24, which have shown the potential to become a Covid-19 treatment. Then, they picked the two medicines that showed antiviral activities in animal models.

The infectious disease experts said they would evaluate ciclesonide, one of the two picked by IPK.

Professor Kim Woo-ju of the Infectious Disease Department of Korea University Guro Hospital said he applied for an investigator-initiated study to test ciclesonide’s clinical effectiveness in Covid-19 patients with mild symptoms. The Ministry of Food and Drug Safety gave the nod on March 27.

Infectious disease department professors at 11 university hospitals are participating in the study.

The clinical trial will enroll 141 mild Covid-19 patients and divide them into three groups — ciclesonide alone group, ciclesonide plus hydroxychloroquine group, and conservative standard treatment group. The patients will be randomly assigned for observation.

Patients will orally inhale ciclesonide 320ug twice a day at 12-hour intervals for 14 days, and hydroxychloroquine 400mg, once daily for 10 days.

Primary endpoints include the negative rate of respiratory virus (on day 7, 14), the time until the virus turns negative (days), the period until clinical improvement (days), and the fraction of clinical failures.

Kim, the principal investigator of the study, said he has been closely monitoring news articles that said ciclesonide was effective in Covid-19 treatment. He said, “The IPK said ciclesonide’s viral suppression in a lab test showed a good outcome and proposed to me that I could do the trial. After discussion within the Korean Society of Infectious Diseases, I decided to lead the study.”

Kim assumed that ciclesonide, which is inhaled orally, would have antiviral and inflammatory control effects locally in the respiratory system. “I assume that it will improve clinical symptoms, shorten the hospitalization period, and prevent the worsening of severe cases by removing the virus quickly in mild patients, rather than in severe patients,” he added.


R_P

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Gender: Male


Posted: Apr 16, 2020 - 5:21pm

Another hill it is...

R_P

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Gender: Male


Posted: Apr 16, 2020 - 12:58pm

 Proclivities wrote:
 
Yes, same thing. Thank. Did not get/notice a paywall block.
Proclivities

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Location: Paris of the Piedmont
Gender: Male


Posted: Apr 16, 2020 - 12:46pm



 R_P wrote:
 
Paywall on that site, but I believe I found it transcribed here: https://www.fr24news.com/a/2020/04/ostrich-alliance-leaders-denying-the-threat-of-coronaviruses.html



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